A brief review on the molecular biology of human adenoviruses

Human adenoviruses infection causes diseases worldwide in all age groups and genders, which is associated with a wide range of affecting the gastrointestinal tract, respiratory urinary eye, but they are often isolated from pharynx stool asymptomatic children. However, developing countries, diarrhea major cause morbidity mortality; after rotaviruses, human considered to be second most important viral infantile diarrhea. Also, fatal acute distress syndrome healthy adults especially infants immune-compromised individuals. This review summarizes both classical contemporary discoveries study at molecular level, particular emphasis on receptors, capsid proteins, nucleic acid, genome properties as well interactions governing virion assembly. In this article, we provide insightful information concerning aspects adenoviruses. would develop an understanding virus serve powerful tool identifying new approaches for prevention treatment adenoviral infection.